RAPD Analysis, Synthesis of Zinc Oxide Nanoparticles Derived from Aerva lanata Flower: Characterization and Antimicrobial Screening

Thamaraiselvi Ganesan1,, Suriyavathana Muthukrishnan1,*,, Braivy Anto1,, Manikandan Mathaiyan1,, Sobiya Pradeep Kumar1,, R. Jayaprakash2, and M. Suganya3,

1Plant Therapeutics Laboratory, Department of Biochemistry, School of Bioscience, Periyar University, Salem-636011, India

2Department of Chemistry, School of Arts and Science, AV Campus, Vinayaka Mission’s Research Foundation (Deemed University), Paiyanoor, Chennai-603104, India

3Department of Biochemistry, Islamiah Women’s Art’s and Science College, Vaniyambadi-635751, India

*Corresponding author: E-mail: suriyaveda@periyaruniversity.ac.in

Abstract

Nanoparticles and plant phytochemicals are receiving great interest between materials and drug discovery studies. Hence, this work report the synthesis of zinc oxide nanoparticles (ZnO NPs) using Pashanabheda (Aerva lanata), which is employed as an antiurolithiatic agent. The selection of the Aerva lanata flower, a member of the Amaranthaceae family, as the source material was based on its ability to exhibit a wide range of genetic modifications in response to various environmental and geographical factors. The synthesized ZnO NPs were characterized by UV, FTIR, XRD and scanning electron microscopy. Due to flower’s chemical make-up and presence of several functional groups in ZnO nanoparticles were found to be effective at bio-reduction and capping. Antibacterial assay against B. subtilis, S. aureus, K. pneumonia and Pseudomonous using ZnONPs of A. lanata flower exhibited excellent inhibition zones between 11 mm and 18 mm for 100 μg/mL.

Keywords

Aerva lanata, RAPD analysis, Green synthesis, ZnO nanoparticle, Antibacterial activity.

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