Reshma^1,2,*,, Hussain Shaik^3,, Konda Manohar^4,, B. Mukesh⁴, Ramana Reddy Boddu^4,, Sravanthi Ittikyala^4, and Puppala Veera Somaiah^1,

¹Department of Chemistry, University College of Science, Osmania University, Tarnaka, Hyderabad-500007, India

²Chemistry Division, Department of Humanities & Sciences, CVR College of Engineering, Hyderabad-501510, India

³Analytical and Structural Chemistry Department, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad-500007, India

⁴Vignan Institute of Technology & Science, Deshmukhi (V), Pochampally (M), Yadadri-Bhuvanagiri District-508284, India

*Corresponding author: E-mail: reshma1947aug15@gmail.com

Silver nanoparticles (AgNPs) were prepared by co-precipitation method using a capping agent, PEG-4000 (polyethylene glycol). The synthesized AgNPs were characterized using UV-visible, FTIR, SEM, EDX and TEM techniques. The bandgap energy of snythesized nanoparticles was determined using UV-visible spectra and found to be 3.07 eV. The particle size of nanoparticles calculated from the TEM and XRD pattern was in the range of 10-23 nm. The degradation efficiency of PEG capped AgNPs towards methylene blue (MB) dye under solar radiation was 63.78%. The photocatalytic degradation of MB dye follows the pseudo-first-order kinetics with an apparent rate constant of 1.1 × 10^-2 min^-1. The degradation products of MB dye during the photocatalytic process were identified using liquid chromatography-mass spectrometry (LC-ESI-TOF-MS). The antibacterial activity of synthesized PEG capped AgNPs using a disc diffusion method against four different Gram-positive and Gram-negative bacterial strains. The results showed that the synthesized nanoparticles could exhibit antibacterial activity. The anticancer activity of synthesized PEG capped AgNPs was tested against cancer cell lines such as A549 and HepG2. The results revealed that the synthesized PEG capped AgNPs have also shown an excellent anticancer activity with increasing their concentration. The antidiabetic activity of PEG capped AgNPs was studied against the α-glucosidase enzyme. The results confirmed that the synthesized AgNPs were shown α-glucosidase inhibition to 45.08%. The ABTS and DPPH radical scavenging activities were used to assay the antioxidant activity of synthesized PEG capped AgNPs.

Silver nanoparticles, PEG-4000, Co-precipitation method, Biological activities, Photodegradation, Methylene blue dye.