| A Facile Catalytic One-Pot Synthesis of Benzimidazole and Benzothiazole Compounds using Amberlite IRA 400-Cl Resin as Green Catalyst |
S. David Amalraj1,*, , G. Harichandran2,, D. Bhakiaraj1,*, and A. Amalorpavadoss1, |
1Chemistry Research Laboratory, P.G. & Research Department of Chemistry, St. Joseph's College of Arts and Science (Autonomous), Cuddalore-607001, India
2Department of Polymer Science, University of Madras, Guindy Campus, Chennai-600025, India
*Corresponding authors: E-mail: daveamalraj@gmail.com; dbhakiaraj@gmail.com |
| Abstract
A series of pharmaceutically valuable functionalized fused heteroaromatic compounds such as benzimidazoles and benzothiazoles have been synthesized via catalytic cyclocondensation between 1,2-phenylenediamine or 2-aminothiophenol and aryl aldehydes at ambient conditions. The Amberlite IRA400-Cl resin have been proved to be an efficient green catalyst in this protocol. The salient features of this method are the mild condition, easy work-up, an excellent yield of product, green catalyst and reusability of the catalyst. |
| Keywords
Cyclocondensation, Amberlite IRA-400 Cl resin, Green catalyst, Benzimidazoles, Benzothiazoles. |
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