Synthesis, Characterization, Biological and Molecular Docking Studies of 1,3-Diphenyl-1H-pyrazole Terminated Imino Derivatives

P.V. Sandhya, K.V. Muhammad Niyas and K.R. Haridas*

Department of Chemistry, School of Chemical Sciences, Kannur University, Payyanur Campus, Edat-670327, India

*Corresponding author: E-mail: chemistryscs@gmail.com

Abstract

Herein, the novel pyrazole derivatives with imino moiety were synthsized, characterized using IR, NMR, mass spectroscopy, elemental analysis and screened their biological activities. Molecular docking studies were also carried out by the software Arguslab 4.0.1. The synthesized compounds showed moderate to good biological activities both experimentally and theoretically.

Keywords

Pyrazole derivatives, Vilsmeier-Haack reaction, Biological activities, Molecular docking.

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