A Simple and Convenient Method for Synthesis of Artemisinin Dimer through Aliphatic Nitro Compounds

Nitin Srivastava1,*,, B.K. Rathore2, R.K. Vishnoi1 and Sangeeta Bajpai1,

1Department of Chemistry, Amity University Uttar Pradesh Lucknow Campus, Lucknow-226028, India

2Department of Chemistry, Fakhruddin Ali Ahmed Government P.G. College, Mahmudabad-261203, India

*Corresponding authors: E-mail: nitinsriv5@gmail.com; sbajpai1@amity.edu


A simple way of synthesis of artemisinin dimer using nitro aliphatic compounds is reported. Herein, few artemisinin monomers and dimers have been synthesized with the help of linker nitroalkanes using iron catalyst supported on polymer (Fe/SBA-15). The synthesized artemisinin shows good anticancer and antimalarial activities.


Substituted aliphatic compounds, Polymer (Fe/SBA-15), Artemisinin dimer, Biological activities.

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