Microwave-Assisted Efficient Synthesis of Spiropyridine Derivatives via Catalyst- and Solvent-Free One Pot Four Component Reaction

Debajyoti Bhuyan

Department of Chemistry, Dergaon Kamal Dowerah College, Dergaon-785614, India

Corresponding author: E-mail: debachem.bhuyan@gmail.com


A microwave-assisted, one-pot four-component reaction strategy has been developed for the synthesis of some novel spiropyridine derivatives from 1,3-dimethyl barbituric acid, chalcone, aromatic aldehyde and ammonium acetate under catalyst- and solvent-free conditions.


Spiropyridine, 1,3-Dimethyl barbituric acid, Chalcone, Multi-component reaction.

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