Synthesis of Dimethyl Octahydroquinazolinones by using Electrochemically Prepared Copper Oxide Nanoparticles

Manisha R. Sawant1,*, Suresh T. Gaikwad2, Bhaskar H. Zaware1 and Anjali S. Rajbhoj2

1Department of Chemistry, New Arts, Commerce and Science College, Ahmednagar-414001, India

2Department of Chemistry, Babasaheb Ambedkar Marathwada University, Aurangabad-431004, India

*Corresponding author: E-mail:


Present work involves the synthesis of substituted dimethyl octahydroquinazolinones by using electrochemically prepared copper oxide nanoparticles as catalyst in microwave. Copper oxide nanoparticles were prepared in appreciable yield by using electrochemical reduction method of synthesis in the presence of tetrabutylphosphonium bromide for capping. The prepared nanoparticles were analyzed by UV, FTIR, TGA, X-ray diffraction and electron microscopic studies. The nanoparticles of copper oxide then were successfully used as a catalyst in multicomponent reaction between diketones, substituted aldehydes and urea/thiourea to synthesize substituted dimethyl octahydroquinazolinones.


Electrochemical reduction, Copper oxide nanoparticles, Tetrabutylphosphonium bromide, Octahydroquinazolinones.

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