Phytochemical Investigations and Antifungal Activity of Bark of Moringa oleifera (Lam.)

Jyoti Punia*, Rajvir Singh and Suman

Department of Chemistry and Biochemistry, College of Basic Sciences and Humanities, Chaudhary Charan Singh Haryana Agricultural University, Hisar-125 004, India

*Corresponding author: E-mail:


Phytochemical study of methanolic extract of bark of Moringa oleifera afforded three compounds viz., 2,11-dihydroxy-12-methoxy lactone, β-sitosterol and xylitol. Out of these, two compounds were new and reported for the first time from Moringa oleifera bark namely, 2,11-dihydroxy-12-methoxy lactone and xylitol. Also the methanolic extract was fractionated using solvents of different polarity. The obtained fractions and methanolic extract were then evaluated for their antifungal activity by poisoned food technique at 250, 500, 1000 and 2000 μg/mL concentrations against two phytopathogenic fungi. All the fractions of bark had shown maximum antifungal activity at 2000 μg/mL concentration against R. solani and F. oxysporum. All the extract/fractions were also more toxic against Rhizoctonia solani than Fusarium oxysporum.


Moringa oleifera, Antifungal activity, Isolation, Phytochemicals, Rhizoctonia solani, Fusarium oxysporum.

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