Brønsted Acidic 1-Ethyl-1,2,4-Trizolium Phenylsulfonate as Catalyst for Biginelli Reaction

G. Puthukkudy1, S. Nagarajan2 and E. Kandasamy1,*

1Department of Sciences, Amrita School of Engineering Coimbatore, Amrita Vishwa Vidyapeetham, Amritanagar, Coimbatore-641 112, India

2Department of Science and Humanities, PSN Engineering College, Melathediyoor-627 152, India

*Corresponding author: Fax: +91 422 2656274; Tel: +91 422 265564; E-mail:;


A Brønsted acidic 1-ethyl-1,2,4-triazolium phenylsulfonate has been synthesized and characterized. A catalytic study is performed for 1-ethyl-1,2,4-triazolium phenylsulfonate as acid catalyst for a multicomponent reaction of synthesis of series of 3,4-dihydropyrimidin-2(1H)-ones/thiones and their derivatives have been employed and the results were discussed in detail.


Biginelli reaction, Dihydropyrimidones/thiones, Triazolium salts, Ionic liquids, Pyrimidones.

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