A Simple and Straightforward Synthesis of Cinnamic acids and Ylidene Malononitriles via Knoevenagel Condensation Employing DABCO as Catalyst

K. Nagalakshmi1,*, B.S. Diwakar2, B. Govindh3, P. Gopal Reddy4, R. Venu5, I. Bhargavi1, T.J. Prasanna Devi1, Y.L.N. Murthy1 and V. Siddaiah1

1Department of Organic Chemistry, Organic Research Labs, Andhra University, Visakhapatnam-530 003, India

2Department of Engineering Chemsitry, SRKR Engineering College (A), Bhimavaram-534 204, India

3Department of H&S, Raghu Institute of Technology, Visakhapatnam-531 162, India

4Shilpa Medicare Limited, Raichur-584 135, India

5School of Engineering Science & Technology, University of Hyderabad, Hyderabad-500 046, India

*Corresponding author: E-mail: nagalakshmi3083@gmail.com

Abstract

An efficient method for the synthesis of substituted cinnamic acid and ylidene malanonitriles is developed via Knoevenagel condensation of aromatic aldehydes with malonic acid and malononitrile in the presence of catalytic amounts of DABCO. This method has many advantages, such as mild reaction conditions, excellent yields, short reaction times and no furthur purification required.

Keywords

DABCO, Aromatic aldehydes, Malonic acid, Malononitrile, Knoevenagel condensation.

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