A Simple, Efficient and Eco-Friendly Synthesis of 2,3-Dihydro-1H-1,5-benzodiazepines Mediated by Tannic Acid under Solvent-Free Condition |
Akshdeep Sandhar and Rajesh K. Singh* |
Pharmaceutical Chemistry Division, Shivalik College of Pharmacy, Nangal-140 126, India
*Corresponding author: E-mail: rksingh244@gmail.com |
Abstract A rapid and efficient environment friendly multicomponent one-pot synthesis of 2,3-dihydro-1H-1,5-benzodiazepines catalyzed by tannic acid has been described under solvent free condition. Simple and effective method, use of non-hazardous and cheap catalyst, much faster reaction time (50-60 min) and good to excellent yields are the important features of this method. |
Keywords One-pot synthesis, 1,5-Benzodiazepines, Tannic acid. |
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