Studies on Antioxidant Activities of Chemical Constituents of Swertia mussotii Franch

Jian-Sheng Zhang1, Xue-Mei Wang2, Yun-Tao Gao1 and Gan-Peng Li1,*

1School of Chemistry and Bio-Technology, Yunnan Nationalities University, Key Laboratory of Chemistry in Ethnic Medicine Resources, Kunming 650031, P.R. China

2Yunnan University Second School, Kunming 650031, P.R. China

*Corresponding author: Fax/Tel: +86 871 5913013; E-mail:


To study the chemical constituents in Swertia mussotii Franch and their scavenging effects of active oxygens species. A new xanthone named 1,7-dihydroxy-2,3,8-trimethoxyxanthone (1), together with 1,8-dihydroxy-2,6-dimethoxyxanthone (2) and sweroside 2'-O-(3,3',5- trihydroxy-2-biphenylcarboxylate (3), were isolated from Swertia mussotii Franch. Their structures were elucidated by spectroscopic methods, including one and two-dimensional NMR (COSY, HMQC, HMBC and ROESY). Scavenging effects of them on active oxygen species ·OH and O2 – generated by Fenton reaction and riboflavine photosensitization in vitro were investigated by the means of spectrophotometry for the first time and the results showed that three compounds could scavenge active oxygen species efficiently.


Swertia mussotii Franch, Fenton reaction, Riboflavine, Active oxygen species.

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  • Asian J. Chem. /
  •  2011 /
  •  23(5) /
  •  pp 1966-1968