Antioxidant Activity and Brine Shrimp Lethality of Tragia involucrata L.¶

MANTENA G. SAVITHRI†, BHUPATIRAJU A.S. CHANDANADEVI†, ALLURI V. KRISHNARAJU, CHIRRAVURI V. RAO and GOLAKOTI TRIMURTULU*

Laila Impex R&D Centre, Unit-I, Phase-III, Jawahar Autonagar, Vijayawada- 520 007, India Fax: (91)(866)2546216; Tel: (91)(866)2541303 E-mail: lailarescen@sify.com; research@lailanutra.com

†College of Life Sciences, DNR College, Bhimavaram-534 202, India.

Abstract

Various extracts of T. involucrata have shown superoxide free radical, DPPH radical scavenging activities and brine shrimp toxicity. Ethyl acetate and methanol extracts showed poor to moderate antioxidant activity. However the aqueous methanol extract showed potent antioxidant activity and the fractions obtained from bioactivity guided fractionation of aqueous methanol extract showed potent antioxidant activity when compared to other extracts of T. involucrata and known commercial antioxidants like BHT, BHA. Methanol and aqueous methanol extracts also showed moderate brine shrimp lethality and fractions obtained from aqueous methanol extracts showed potent brine shrimp toxicity.

Keywords

Antioxidant activity, Tragia involucrata, BHA, BHT, Artemia salina, Brine shrimp lethality.
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  • Asian J. Chem. /
  •  2010 /
  •  22(3) /
  •  pp 1684-1688