| Spectrophotometric Analysis of Nitazoxanide in Single and Combined Dosage Form |
S HAILENDRA PANDEY , RAVI |
Department of Pharmacy, Shri Govindram Seksaria Institute of Technology & Science, Indore-452 003, India E-mail: ravishukla2007@gmail.com; meenatiwari2004@yahoo.co.in |
| Abstract
Two simple sensitive UV spectrophotometric methods for the analysis
of nitazoxanide in single and in combined dosage form with ofloxacin
were developed and statistically validated. Estimation of nitazoxanide
in tablet dosage form was carried out by calibration curve method while
graphical absorbance ratio method was used for nitazoxanide and
ofloxacin combined tablets. The absorption maxima (lmax) for
nitazoxanide and ofloxacin are 268 and 302 nm, respectively. The most
striking feature of this method is its simplicity, sensitivity and reproducibility.
The method is economical and suitable for routine analysis
of nitazoxanide tablets and nitazoxanide and ofloxacin in combined
tablet dosage form. |
| Keywords
Spectrophotometric Analysis, Nitazoxanide. |
| |
View Article 
This work is licensed under a Creative Commons Attribution 4.0 International License.
|
|
|
|