Reaction of 4-Arylmethylnen-2-Phenyl-2-Oxazolin-5-Ones with Schiff bases and Benzalazine

M. Fekry Ismail and N. Gharib Kandile*
  Chemistry Department, Faculty of Science University College for Women, Ain Shams University Helipolis, Cairo, Egypt

4-Arylmethylene-2-phenyl-2-oxazolin-5-ones (1) react with schiff bases in benzene to give the arylamides of α-carboxamido-,β-arylacrylic acids (2). However the reaction of 1 with schiff bases in acetic acid containing catalytic amounts of fused sodium acetate gave 1, 2-diaryl-4-arylmethylene- 2-imidazolin-5-ones (3). Reaction of benzalazine with 1a in benzene or in the absence of solvent involved cleavage of one of the imino groups yielding 4 and 5 respectively. The. structures of the products were confirmed by analytical and spectral data and also by synthesis of authentic samples in most cases.


   View Article PDF File Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
  • Asian J. Chem. /
  •  1989 /
  •  1(3) /
  •  pp 254-260