Synthesis of 2-Methyl/phenyl-3-[(4-substituted-benzylidene) Amino-phenyl]-6 & 8-disubstituted-1,3-quinazolin-4-ones as Potenital Anthelmintic Agents

J. S. Shukla and M. Fadayan*
Department of Chemistry, LucknowUniversity, Lucknow 226 007 India

Thirty 2-Methyl/phenyl-3-[(4-substituted-benzylidene) amino-phenyl]-6&8-disubstituted-quinazoline-4-ones were synthesised and screened for their anthelmintic activity aganist Hymenolepis nanainfection in mice and Nippostrangylus brasilliensis infection in rat. Some of the compounds were also tested for their antiviral and antibacterial activity.


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  • Asian J. Chem. /
  •  1989 /
  •  1(3) /
  •  pp 208-213