Studies on Trimethoxy Indan-1-yl-acetic Acids as Anti-hyperchlestrolemic Agents |
MANORANJAN ADAK† and JAYANTA KUMAR GUPTA* |
Division of Medicinal Chemistry, Department of Pharmaceutical Technology
Jadavpur University, Kolkata-700 032, India
E-mail: manoranjanadak@rediffmail.com |
Abstract Trimethoxy indan derivatives having (R = alkyl group) at the α-carbon atom of acetic acid moiety were synthesized and screened for anti-hypercholesterolemic activity in male albino Charles Foster rats. It was observed that percentage yield as well as pharmacological activity of synthesized compounds decreased on increasing the α-alkyl group. |
Keywords Trimethoxy indan acetic acids, Clofibrate, Antihypercholesterolemic activity. |
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